Translational Research: Applying Discovery

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In vivo Antisense Oligonucleotide Reduction of NPC1 Expression as a Novel Mouse Model for Niemann Pick Type C Associated Liver Disease Rimkunas, Graham, Crooke, Liscum
Activation of the Calcium Sensing Receptor Stimulates Serum Gastrin and Gastric Acid Secretion in Healthy Subjects Ceglia, Harris, Rasmussen, Dawson-Hughes
Breast Cancer Metastasis to Bone: Modeling Angiogenesis in the CAM using Tissue Engineering Strategies Reagan
A Mouse Model of Human Breast Cancer Metastasis to Tissue-Engineered Bone Faverman, Moreau, Anderson, Reagan, Kaplan, Rosenblatt
Mouse Models of Human Cancer Metastasis Revealing Osteotropism Gene Signatures Goldstein, Anderson, Moreau, Rosenblatt
Silencing of a Stem Cell Differentiation Gene (APRIN) in Prostate and Breast Cancers: Promoter Methylation and Microrna Clinical Studies Pilichowska, Denes, Kyu Kim, Makarovskiy, Carpinito, Geck
Apoptosis in Response to Inhibition of Dipeptidyl Peptidase 2 Defines Low Risk Chronic Lymphocytic Leukemia Danilov, Danilova, Klein, Huber
Transfection with mRNA for CD19 Specific Chimeric Antigen Receptor Restores NK Cell Mediated Killing of CLL Cells Boissel, Betancur, Tuncer, Weitzman, Klingemann
Variable Contribution of Different Monoclonal Antibodies to NK Cell-Mediated ADCC Against Primary CLL Cells Weitzman, Klingemann, Betancur, Boissel, Rabinowitz
Modulation of Lung Molecular Biomarkers by β-Carotene in the Physicians’ Health Study Liu, Gaziano, Mucci, Wang, Zhang
Inhibitors of STAT3 Prevent Proliferation of Brain Tumor Stem Cells Sherry, Reeves, Wu, Cochran
G Protein-Activated Inward Rectifier Potassium Channel 4 is a Regulateable Protein; Its Role in Autonomic Neuropathy in Type I Diabetes Zhang, Park, Madias, Aronovitz, Karas, Galper
Simvastatin Inhibits Angiotensin II-Induced Abdominal Aortic Aneurysm Formation in Apolipoprotein E Knockout Mice Zhang, Naggar, Moulton, Park, Galper
Myosin Phosphatase-Rho Interacting Protein Modulation of Vascular Smooth Muscle Phenotype Crochiere and Surks
Morphometric Measurements and Insulin-Like Growth Factor in Cats with Spontaneously-Occurring Hypertrophic Cardiomyopathy Yang, Freeman, Rush
The Obesity Paradox in Dogs with Spontaneously-Occurring Heart Failure Slupe, Freeman, Rush
Relationship between Cachexia and Lymphocyte Subpopulations and Hematologic Parameters in Dogs with Spontaneously-Occurring Congestive Heart Failure Freeman and Rush
A Comparison of Oral Versus Transdermal Atenolol Administration in Cats MacGregor, Rush, Rozanski, Boothe, Belmonte, Freeman
Lipid Lowering by Pravastatin Decreases Premature Ventricular Contractions and Ventricular Tachycardia: Gαi2, a Possible Molecular Marker for Predisposition to Arrhythmia Welzig, Park, Naggar, Karas, Estes, Galper
Preliminary Foundation for in vitro Autosomal-Dominant Polycystic Kidney Disease Model Rudym, Kaplan, Perrone
Mitochondrial Membrane Potential in Single Cells in Chronic Kidney Disease – Application of the Live Cell Array Sathi, Padala, Rao, Demello, Arvold, Wikstrom, Molina, Haigh, Balakrishnan, Shirihai
Comparative Analysis of Urinary Biomarkers for the Early Detection of Acute Kidney Injury (AKI) Following Cardiopulmonary Bypass (CPB) Liangos, Perianayagam, Kolyada, Tighiouart, MacKinnon, Wald, Han, Bonventre, Jaber
Proteomic Research and Services of the Tufts Proteomic Core Facility DeGnore
STAT Decoy Oligonucleotide Administration Decreases Airway Inflammation and AHR in Allergic Asthma Simeone-Penney and Simon
Nucleic Acid Microsphere Arrays for Respiratory Pathogen Analysis Hayman and Walt
Intra-Oral Biofilms in the Complete Denture-Wearing Patient Sachdeo
Substance P Stimulates Human Mast Cells and Together They Activate T Cells: Inhibition by Luteolin Kempuraj, Tagen, Iliopoulou, Clemons, Vasiadi, Boucher, House, Wolfberg, Theoharides
Microsphere-Based Cytokine Array for Salivary Diagnostics Blicharz and Walt
Subtilase Cytotoxin (SubAB), a Newly-discovered Cytotoxin Produced by Certain Shiga Toxin-producing Escherichia coli (STEC) Induces a Stress Response in the Endoplasmic Reticulum Wolfson, May, Thorpe, Jandhyala, J. Paton,
A. Paton
Tufts Center for Integrated Tissue Engineering: Translational 3D Human Tissues for Drug Discovery Egles, Shamis, Garlick
Cell Penetrating Peptide for Delivery of DNA, siRNA and Quantum Dots in vitro and in vivo Johnson, Cashman,
Pomegranate Juice Does Not Impair Clearance of Oral or Intravenous Midazolam: Comparison with Grapefruit Juice Farkas, Oleson, Zhao, Harmatz, Zinny, Court, Greenblatt
The Effect of Ritonavir and Chronic Viral Hepatitis on Cytochrome 3A Activity in HIV Infected Patients Oleson, Knox, von Moltke, Kaufman, Greenblatt
Sleep Duration and Overweight in Early Elementary School Children Hennessy, Kuder, Goldberg, Must, Sacheck, Economos
Children's Multiple Representation of Their Ideas about Science Gravel
Transforming Science Learning in the Elementary Grades Through LEGO™ Engineering Design Jarvin, Rogers,
Bethke Wendell, Wright
The Child and Adolescent Scale of Participation (CASP): Further Psychometric Testing Bedell
Translating Community-Based Asthma Research in Boston Chinatown into a Community-Based Program Palella, Chin, Lane, Brugge
A Model for Clinical Evaluation of Perioperative Analgesia in the Rabbit Karas, Weaver, Andrutis, Blaze
Bioinformatics Identifies 107 Candidate Transcription Factors Involved in Fat Storage Lane, Parnell, Ordovas
Central Dopamine Deficits as Markers for Dietary Obesity Predisposition Geiger, Frank, Caldera-Siu, Beinfeld, Pothos
Exposure to Low Frequency Magnetic Fields Alters Catecholamine Exocytosis Saveriades, Dunlap, Theoharides, Sergiadis, Pothos
Chronic Morphine Exposure in Peripubertal Female Rats Results in Altered Opioid Sensitivity and Tolerance in Their Offspring E. Byrnes, Babb, Scanlan, J. Byrnes
Cell Cycle Re-entry and the Role of Molecular Chaperones in β-Amyloid Laden Skeletal Muscle Cells and Alzheimer’s Disease Brain Kumar, Fu, Lee, Querfurth
Changes in Expression and Chromatin Structure of the Mental Retardation Gene Jarid1c in Neural Differentiation Xu, Arnold , Disteche
Assessment of Sleep Disorders in Patients with Chronic Orofacial Pain Lobo Lobo, Chandwani, Kulich, Mehta, Scrivani
Gold Nanocatalysts for Clean Energy Production Flytzani-Stephanopoulos, Deng, Si, Zhai
Detection of Biomolecules by Magnetic Reporting of Magnetically Labeled Nanorods Harrah, Xie, Oh, Naughton, Sun, Guertin, Goldberg
Experimental Techniques for Understanding Chemical Mechanical Polishing Gray, Vlahakis, Braun, Rogers, Manno
Reproductive Experience Increases Neural Prolactin Receptor and Socs-1 and -3 mRNA Expression in the Rostral Hypothalamus of Female Rats Bridges, Anderson,
van der Ancker, Grattan
Arginine Vasopressin Antagonism Affects Maternal Aggression and the Retention of Maternal Behavior in Lactating Rats Nephew and Bridges
The Mechanical Properties of Caterpillar Cuticle Lin, Dorfmann, Trimmer
Occipitocervical Fusion in a Dog Using Locking Buttress Plate Fixation and Synthetic Bone Graft (rhBMP-2 CRM) Boudrieau and Faissler
Predictors of Mobility-Disability in Older Adults: The Role of Lower Extremity Muscle Strength and Body Composition Reid, Naumova, Carabello, Phillips, Frontera, Fielding
Slow Rate of Neuromuscular Activation Contributes to Impaired Movement Acceleration and Peak Power in Mobility-Limited Older Adults Clark, Patten, Reid, Carabello, Phillips, Fielding
Effect of Almond Skin Polyphenols and Quercetin on Human LDL and Apolipoprotein B-100 Oxidation and Conformation Chen and Blumberg
Almond Consumption Reduces Oxidative DNA Damage and Lipid Peroxidation in Male Smokers Chen, Jia, Li, Blumberg
Rock1, Rock2 and a Little Rock: Can a Little Gene Make the Difference? Montefusco, Wooten, Huggins



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